With Horizon Exchange, where a range of zAssets are introduced into Horizon Protocol, you will need to understand that your debt obligation to the system is proportionally based, meaning the system tracks the percentage of your debt relative to the global debt. Because of this, when the prices of the assets in the global debt portfolio change, so does your debt obligation. If you are 1% of the global debt with $1000 in debt, and the average price of all assets in the global portfolio increases by 10% (which also means the global debt is increased by 10%), then your debt obligation will also increase and become $1100. If the synthetic assets you hold do not also increase by 10%, then you will incur a loss (assuming the global debt doesn't shrink back later).